It is one of, if not the most, expensive states in the country. When you add crazy high state and local taxes it's got to be difficult. I've worked in 47 states and San Diego is my favorite city in the country. I absolutely love it. But I couldn't come close to having the same quality of life if I lived there.

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Yes, Scilex Holding Co is a real company. It’s a biopharmaceutical firm specializing in acquiring, developing, and commercializing non-opioid pain management products for acute and chronic pain. Key details include: • Headquarters: 960 San Antonio Road, Palo Alto, CA 94303, USA. • Founded/Listed: Publicly traded on Nasdaq under the ticker SCLX since November 11, 2022. • Products: Their commercial product is ZTlido (lidocaine topical system) for postherpetic neuralgia. They’re also advancing candidates like SEMDEXA (SP-102), a triple-strength ZTlido (SP-103), and SP-104 (low-dose naltrexone). • Employees: Approximately 31. • Website: scilexholding.com. This information is based on current financial market data as of November 2025.

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winter coming, time for san diego

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San Francisco homeless camp

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Wow META sucks so much that Facebook decided to reset my facebook marketplace location, same for my coworker to San Francisco instead of Montreal, Canada. WTF!

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>NOT EVEN A 0% INTEREST RATE WOULD MAKE A TYPICAL HOME AFFORDABLE IN NEW YORK, LOS ANGELES, MIAMI, SAN FRANCISCO, SAN DIEGO, OR SAN JOSE, PER ZILLOW. 😬

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Have to head to San Antonio.

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Ahh, the San Quentin special

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San Francisco is safer than Paris, France

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when i ate tacos frequently, i used to go to this place, el zarape, in san diego, and order the fish taco. there was this other amazing place near the border, where you could get all kinds of taco, like birria and whatnot. and it was like a parking lot with metal chairs. then i moved away. and i get tacos here and there, but not as good :/

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